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Peripheral muscle strength and functional capacity in patients with moderate to severe asthma.

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Title: Peripheral muscle strength and functional capacity in patients with moderate to severe asthma.
Author(s): Ramos, E; de Oliveira, LV; Silva, AB; Costa, IP; Corrêa, JC; Costa, D; Alves, VL; Donner, CF; Stirbulov, R; Arena, R; Sampaio, LM
Subject(s): Asthma Functional capacity Obesity Physical activity
Abstract: BACKGROUND: The adequate control of asthma includes the absence of nocturnal symptoms, minimal use of medication, normal or nearly normal lung function and no limitations to physical activity. The choice of a more sedentary lifestyle can lead to physical de-conditioning, thereby aggravating asthma symptoms and increasing the risk of obesity. METHODS: This study aimed at performing a battery of function-related assessments in patients with asthma and comparing them to a healthy control group. A prospective, transversal and case-control study was designed. It was set up at Santa Casa de Misericórdia Hospital -Sao Paulo and Nove de Julho University on a population of outpatients. Subjects of the study were patients affected by moderate to severe asthma. A case-control study was carried out involving 20 patients with moderate to severe asthma and 15 healthy individuals (control group). All participants underwent body composition analysis (BMI and BIA) and a controlled walk test (Shuttle test), resistance muscle test (1RM) and answered a physical activity questionnaire (IPAQ). The group with asthma also answered a questionnaire addressing the clinical control of the illness (ACQ). RESULTS: In comparison to the control group (unpaired Student's t-test), the patients with asthma had a significantly higher BMI (31.09 ± 5.98 vs. 26.68 ± 7.56 kg/m(2)) and percentage of body fat (38.40 ± 6.75 vs. 33.28 ± 8.23%) as well as significantly lower values regarding distance traveled on the walk test (369 ± 110 vs. 494 ± 85 meters) and metabolic equivalents (3.74 ± 0.87 vs. 4.72 ± 0.60). A strong correlation was found between the distance completed and peripheral muscle strength (r: 0.57, p < 0.05) and METs (Metabolic equivalents - minutes/week) and peripheral muscle strength of 1RM (r: 0.61, p = 0.009). CONCLUSIONS: The individuals with asthma had lower functional capacity and levels of physical activity as well as a higher percentage of body fat compared to healthy individuals. This suggests that such patients have a reduced physical performance stemming from a sedentary lifestyle. Despite the existence of few studies reporting moderate to severe asthmatic patients and functional capacity assessment, it is clear that the assessment presented in the current study is a valid and accessible tool in clinical practice.
Issue Date: 2015-01-01
Publisher: BioMed Central
Citation Info: Ramos, E., De Oliveira, L. V. F., Silva, A. B., Costa, I. P., Corrêa, J. C. F., Costa, D., Alves, V. L., Donner, C. F., Stirbulov, R., Arena, R. and Sampaio, L. M. Peripheral muscle strength and functional capacity in patients with moderate to severe asthma. Multidisciplinary Respiratory Medicine. 2015. 10(1). DOI: 10.1186/2049-6958-10-3.
Type: Article
Description: This is a copy of an article published in Multidisciplinary Respiratory Medicine © 2015 BioMed Central Publications.
URI: http://hdl.handle.net/10027/20515
ISSN: 2049-6958
Date Available in INDIGO: 2016-05-04
 

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