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The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer.

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Title: The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer.
Author(s): Muralidhar, GG; Barbolina, MV
Subject(s): chemoresistance expression metastasis miR-200 family ovarian carcinoma
Abstract: The role of microRNAs (miRNAs or miRs) in the pathology of epithelial ovarian cancer (EOC) has been extensively studied. Many miRNAs differentially expressed in EOC as compared to normal controls have been identified, prompting further inquiry into their role in the disease. miRNAs belonging to the miR-200 family have repeatedly surfaced over multiple profiling studies. In this review, we attempt to consolidate the data from different studies and highlight mechanisms by which these miRNAs influence progression of metastasis and chemo-resistance in EOC.
Issue Date: 2015-07-24
Publisher: MDPI
Citation Info: Muralidhar, G. G. and Barbolina, M. V. The miR-200 family: Versatile players in epithelial ovarian cancer. Int J Mol Sci. 2015. 16(8): 16833-16847. DOI: 10.3390/ijms160816833.
Type: Article
Description: This is the copy of an article published in the International Journal of Molecular Sciences © 2015 MDPI Publications.
ISSN: 1422-0067
Sponsor: We gratefully acknowledge financial support by the Ovarian Cancer Research Fund Liz Tilberis Award (MVB).
Date Available in INDIGO: 2016-01-21

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