INDIGO Home University of Illinois at Urbana-Champaign logo uic building uic pavilion uic student center

Effect of Hard Tissue Modification on Bacterial-Induced Secondary Caries at the Tooth-Resin Interface

Show full item record

Bookmark or cite this item: http://hdl.handle.net/10027/19576

Files in this item

File Description Format
PDF Kim_GoEun.pdf (783KB) (no description provided) PDF
Title: Effect of Hard Tissue Modification on Bacterial-Induced Secondary Caries at the Tooth-Resin Interface
Author(s): Kim, Go Eun
Advisor(s): Bedran-Russo, Ana
Contributor(s): Wu, Christine; Viana, Maria
Department / Program: Restorative Dentistry
Graduate Major: Oral Sciences
Degree Granting Institution: University of Illinois at Chicago
Degree: MS, Master of Science
Genre: Masters
Subject(s): resin composite secondary caries grape seed extract dentin biomodification
Abstract: Secondary caries at the tooth-resin interface is the primary reason for replacement of resin composite restorations. The tooth-resin interface is formed by interlocking of resin material with hydroxyapatite crystals in enamel and collagen mesh structure in dentin. Efforts have been made to strengthen the tooth-resin interface, and dentin biomodification agents have been previously identified with collagen cross-linking potential and antimicrobial activities. The purpose of the current study was to assess protective effects of dentin biomodification agents against secondary caries development around enamel and dentin margins of a class V restoration, using a bacterial caries model. Class V composite restorations were made on sixty bovine tooth samples (n=15) with pre-treatment of cavity walls with either control buffer solution, an enriched fraction of grape seed extract (GSE-UP), 1-ethyl-3-(3-dimethyl aminopropyl)-carbodiimide/N-hydroxysuccinimide (EDC/NHS), or chlorhexidine digluconate (CHX). After incubating specimens in a bacterial model with Streptococcus mutans for 4 days, caries lesions were evaluated by microhardness test and confocal laser scanning microscopy with rhodamine B staining. Results of the study revealed that GSE-UP significantly inhibited secondary caries development immediately adjacent to the dentin-resin interface, as indicated by absence of rhodamine B staining around the restoration margin in dentin. Results suggest that incorporation of biomodification agents, specifically GSE-UP, into adhesive systems may inhibit secondary caries and thereby increase the longevity of resin composite restorations.
Issue Date: 2015-07-21
Genre: thesis
URI: http://hdl.handle.net/10027/19576
Rights Information: Copyright 2015 Go Eun Kim
Date Available in INDIGO: 2017-07-22
Date Deposited: 2015-05
 

This item appears in the following Collection(s)

Show full item record

Statistics

Country Code Views
United States of America 284
China 76
Russian Federation 33
Ukraine 17
Germany 15

Browse

My Account

Information

Access Key