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Nanotechnology in Corneal Neovascularization Therapy—A Review

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Title: Nanotechnology in Corneal Neovascularization Therapy—A Review
Author(s): Gonzalez, Lilian; Loza, Raymond J.; Han, Kyu-Yeon; Sunoqrot, Suhair; Cunningham, Christy; Purta, Patryk; Drake, James; Jain, Sandeep; Hong, Seungpyo; Chang, Jin-Hong
Abstract: Nanotechnology is an up-and-coming branch of science that studies and designs materials with at least one dimension sized from 1-100 nm. These nanomaterials have unique functions at the cellular, atomic, and molecular levels. 1 The term "nanotechnology" was first coined in 1974.(2) Since then, it has evolved dramatically and now consists of distinct and independent scientific fields. Nanotechnology is a highly studied topic of interest, as nanoparticles can be applied to various fields ranging from medicine and pharmacology, to chemistry and agriculture, to environmental science and consumer goods. 3 The rapidly evolving field of nanomedicine incorporates nanotechnology with medical applications, seeking to give rise to new diagnostic means, treatments, and tools. Over the past two decades, numerous studies that underscore the successful fusion of nanotechnology with novel medical applications have emerged. This has given rise to promising new therapies for a variety of diseases, especially cancer. It is becoming abundantly clear that nanotechnology has found a place in the medical field by providing new and more efficient ways to deliver treatment. Ophthalmology can also stand to benefit significantly from the advances in nanotechnology research. As it relates to the eye, research in the nanomedicine field has been particularly focused on developing various treatments to prevent and/or reduce corneal neovascularization among other ophthalmologic disorders. This review article aims to provide an overview of corneal neovascularization, currently available treatments, and where nanotechnology comes into play.
Issue Date: 2013-03
Publisher: Mary Ann Liebert
Citation Info: Gonzalez, L., Loza, R. J., Han, K. Y., Sunoqrot, S., Cunningham, C., Purta, P., Drake, J., Jain, S., Hong, S. and Chang, J. H. Nanotechnology in Corneal Neovascularization Therapy-A Review. Journal of Ocular Pharmacology and Therapeutics. 2013. 29(2): 124-134. DOI: 10.1089/jop.2012.0158
Type: Article
Description: This is a copy of an article published in the Journal of Ocular Pharmacology and Therapeutics © 2013 Copyright Mary Ann Liebert, Inc.; Journal of Ocular Pharmacology and Therapeutics is available online at:
ISSN: 1080-7683
Sponsor: This work was partially supported by National Institutes of Health grants UL1TR000050 and EY001792 and EY021886 (JHC) and an unrestricted grant from Research to Prevent Blindness, New York, NY.
Date Available in INDIGO: 2014-01-02

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